CBD history

Brief History of Cannabidiol

Brief History of Cannabidiol

CBD history

  • Cannabis has been cultivated for its medicinal, psychoactive, and physical properties for thousands of years
  • The earliest recorded medicinal uses of the plant date as far back as 1400-2000 BC
  • In the 19th century, William Osler, M.D., considered to be a “Father of Modern Medicine”, was a proponent of the medicinal use of cannabis
  • CBD was first discovered by Dr. Roger Adams and his team at the University of Illinois in 1940 but it’s chemical structure wasn’t elucidated until 1963
  • Dr. Raphael Mechoulam, considered the ‘Father of Cannabis Research’, is recognized for this, as well as the isolation of THC and discovery of the brain’s endogenous cannabinoid
  • While CBD was discovered more than 20 years earlier, THC has dominated cannabis research until recently

Cannabinoids

  • There are 2 primary, endogenous endocannabinoids:  anandamide (AEA), taken from the Sanskrit word ananda, which means "joy, bliss" and 2-arachidonyl glycerol (2-AG)
  • Cannabinoids exert their activity via a specific system of cellular receptors widely distributed throughout the body referred to as the endocannabinoid system
  • THC and CBD, are the most abundant of the > 80 active exogenous cannabinoids within the cannabis plant, collectively referred to as phytocannabinoids
  • Phytocannabinoid pharmacology is still not completely understood, but there appears to be a balancing effect between THC and CBD

cbd cannabinoids

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